extracorporeal circulations การใช้

• The introduction of extracorporeal circulation has facilitated open heart surgery.
• The first open heart procedures with extracorporeal circulation were performed at the beginning of 1962.
• In 1937 Gibbon reports the first successful use of extracorporeal circulation in animals ( in this case, cats ).
• The development of modern techniques in extracorporeal circulation is the result of the combined efforts of physiologists, physicians, and engineers.
• UD requires the establishment of an extracorporeal circulation through its unique AV loop with two pre-existing arterial and central venous lines in ICU patients.
• It has been shown to inhibit intrinsic coagulation, inhibit host responses to extracorporeal circulation, and lessen postperfusion, or  pumphead,  syndrome.
• During the first half of the 20th century scientists refined their methods in the development of extracorporeal circulation so that it could be used in humans.
• John Heysham Gibbon at Jefferson Medical School in Philadelphia reported in 1953 the first successful use of extracorporeal circulation by means of an oxygenator, but he abandoned the method, disappointed by subsequent failures.
• Dr . John Heysham Gibbon at Jefferson Medical School in Philadelphia reported in 1953 the first successful use of extracorporeal circulation by means of an oxygenator, but he abandoned the method, disappointed by subsequent failures.
• During 1961 and 1962 in Romania, he conducted, with his team, extensive experimental and clinical work on the physiology of organisms under deep hypothermia, with the aid of extracorporeal circulation, in animals and in man.
• This required an extensive series of endocardial ( from the inside of the heart ) incisions through both atria, a median sternotomy ( vertical incision through the breastbone ) and cardiopulmonary bypass ( heart-lung machine; extracorporeal circulation ).
• The first commercial minimized extracorporeal circulation was the CorX System from Cardiovention, a start-up company from the USA . This system included an integrated centrifugal pump  polypropylene oxygenator, a complete heparin-coated surface and a low priming volume.
• The benefits of this type of extracorporeal circulation are that a lower consumption of blood and blood products is observed in the peri-operative and post-operative phase and that a lower inflammatory response is being measured in peri-operative blood samples in comparison to conventional cardiopulmonary bypass.